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The Allen Institute for AI (abbreviated AI2) is a research institute founded by late Microsoft co-founder Paul Allen. The institute seeks to achieve scientific breakthroughs by constructing AI systems with reasoning, learning, and reading capabilities.
Description from dendrites.org:
We are interested in understanding computations in neural circuits of the mammalian brain. To attack this problem we work at the interface between cellular and systems neuroscience: we aim to understand the cellular toolkit that enables single neurons to perform computations, and in turn how single neurons and their patterns of connections contribute to the computations performed by neural circuits. Our lab has a special focus on neuronal dendrites, which actively transform synaptic inputs into specific neuronal output patterns. We use the cerebellum and neocortex as model systems, combining in vitro and in vivo imaging and electrophysiology approaches, and taking advantage of a range of high-tech approaches. These include two-photon microscopy, optogenetics, patch-clamp recordings from dendrites, recordings using Neuropixels probes, and most recently the development of 'all-optical' approaches for simultaneous readout and manipulation of neurons by combining two-photon imaging and two-photon optogenetics. Our experiments are complemented by computational models of single neurons and networks of neurons. At each stage of our work, our aim is to link different levels of brain function, in order to reveal how activity in single neurons and neural circuits drives behaviour and, importantly, what kinds of changes take place within these circuits during learning.
Description from alleninstitute.org:
Our mission is to accelerate the understanding of how the human brain works in health and disease. Using a big science approach, we generate useful public resources, drive technological and analytical advances, and discover fundamental brain properties through integration of experiments, modeling and theory.
Description from usc.edu:
The USC Mark and Mary Stevens Neuroimaging and Informatics Institute applies innovative imaging and information technologies to the study of the brain. Our interdisciplinary team investigates brain structure, function and disease, using techniques such as mathematics, genomic analysis and ultra-high-field MRI scanning. Directed by Provost Professor Arthur W. Toga, the institute is housed within Stevens Hall of Neuroimaging, a dedicated, custom-built facility at the Keck School of Medicine of USC.
The Blue Brain Project is a Swiss brain research initiative that aims to create a digital reconstruction of rodent and eventually human brains by reverse-engineering mammalian brain circuitry. The project was founded in May 2005 by the Brain and Mind Institute of École Polytechnique Fédérale de Lausanne (EPFL) in Switzerland. Its mission is to use biologically-detailed digital reconstructions and simulations of the mammalian brain to identify the fundamental principles of brain structure and function.